R. Barry Holtz, Ph.D.

Dr. Barry Holtz is the principal consultant at Holtz Biopharma Consulting, a founding member of the Klyo Collaborative. He has extensive expertise in providing consulting services to the biopharmaceutical development and manufacturing industry including facilities design, process development and quality systems development.

Barry was the Co-Founder of G-CON Manufacturing, maker of autonomous cleanrooms and Caliber Biotherapeutics, developer and manufacturer of plant-made biotherapeutics. Barry was the Senior Vice President of Biopharmaceutical Development for Large Scale Biology Corporation (LSBC) for 15 years and was an integral member of the management team that successfully took the company from a start-up to a publicly-traded company. While at LSBC, Barry was responsible for the product development, long-term regulatory strategy, and clinical development and manufacturing compliance of the company’s proprietary therapeutics portfolio.

Barry has held research management positions at Foremost-McKesson and was on the faculty of Ohio State University. He received his Ph.D. at Pennsylvania State University and was an NSF Postdoctoral Fellow at Scripps Institution of Oceanography. Barry has been awarded 23 U.S. patents and has published more than 50 scientific papers. He was awarded the Pennsylvania State University, Outstanding Alumni Award in 2003.

Some of Dr. Holtz's achievements include:

• Being one the early pioneers in plant-made-pharmaceuticals

• Developing anti-cancer vaccines and therapies

• Designing and commissioning multiple patient-specific cancer therapy manufacturing sites

• Successfully designing, constructing, and commissioning three major greenfield manufacturing sites.

• Founder and inventor of the POD concept (modular, transportable clean rooms) for pharma manufacturing

• Bioreactor design and digital bioreactor control systems

• 23 issued US patents in bioproducts and bioprocesses