Bill Brydges was one of the original leadership members of bioKinetics, the first bioengineering EPCmV, Turnkey Design/Build firm in the U.S. which became a renowned biopharma project engineering firm. He remained as President of Foster-Wheeler Biokinetics after they merged with Foster-Wheeler.
Here are some of the projects Bill Brydges has led:
- Project Manager responsible for the Engineering, Procurement, Construction and Validation of a $100 million Biopharmaceutical facility for Eli Lilly located in Carolina, Puerto Rico. This project included a complete upgrade of plant and clean utilities and development of a new site for solid dosage manufacturing, fill finish operations and an automated warehouse.
- Project Manager responsible for the Engineering, Procurement, Construction and Validation of a $42 million combination biopharmaceutical pilot plant, GMP clinical production, and QC laboratory building for Berlex Biosciences in Richmond, California, USA.
- Project Manager responsible for the Engineering, Procurement and Construction Management and Validation Interface of a $16 million expansion of an existing bioprocess facility for Bayer in Berkeley, California, USA. This was phased construction in order to maintain the integrity of the existing manufacturing operations while construction was simultaneously completed.
- Project Manager responsible for the Engineering and Procurement of a $300 million multiproduct biotechnology production facility for Ares Serono in Vevey, Switzerland.
- Project Manager responsible for the Engineering, Procurement, Construction Management Interface and Validation of a $35 million multiproduct parenteral pilot plant and solid dosage production/ fill finish facility for Eisai Pharmaceuticals. This facility was located in Research Triangle Park, North Carolina, USA. This was a grass roots site.
Bill Brydges and Barry Holtz worked together on an innovative modular oral solid dosage tableting facility for Pfizer called the Pfizer PCMM project. This facility produces 500 million tablets per year. The facility won an Interphex technology award and an ISPE Facility of the Year (FOYA) award for its innovative approach: it was portable to any place on the planet that needed OSD tableting and could be assembled in three days.